Research & Projects
Original work at the intersection of space biology, genomics, and STEM communication.
From microgravity diagnostics aboard the International Space Station to computational CRISPR optimization and a documentary on gene editing, Aryash Shyam pursues science that asks difficult questions and communicates the answers to broad audiences. His research spans laboratory design, computational sequence analysis, documentary filmmaking, and science writing -- output that signals both technical depth and the rare ability to translate complex ideas for general and expert audiences alike.
SPACE BIOLOGY · MICROGRAVITY DIAGNOSTICS
Genes in Space -- 2026 Junior Scientist Award
What happens to biological diagnostics when gravity disappears? Aryash explored this question through the Genes in Space program, designing a microgravity biology experiment aimed at understanding how space conditions affect living systems. His work was recognized with the 2026 Genes in Space Junior Scientist Award, one of the most competitive honors available to student researchers in space biology.
COMPUTATIONAL BIOLOGY · GENE EDITING
Computational gRNA Optimization for CRISPR
CRISPR gene editing depends on a short molecule called a guide RNA (gRNA) that directs the editing machinery to exactly the right place on the genome -- and getting that targeting right is one of the field's central challenges. Aryash tackled this computationally, developing methods to identify and optimize gRNA sequences for maximum precision. Reducing off-target edits is critical for moving CRISPR toward safe therapeutic use, and computational approaches allow researchers to screen thousands of candidates rapidly before any lab experiment begins.
DOCUMENTARY FILM · SCIENCE COMMUNICATION
Editing Humanity: A CRISPR Conundrum
Aryash created Editing Humanity: A CRISPR Conundrum, a documentary on the science and ethics of gene editing told through conversations with researchers, scientists, and people directly affected by emerging technologies. The documentary goes beyond textbook CRISPR explanations to explore what it means when science can rewrite the human genome -- interviewing the people living at the intersection of discovery and consequence. It represents Aryash's commitment to science communication that is both rigorous and deeply human.
AEROSPACE SCIENCE · SCIENTIFIC WRITING
First Place -- NASA 2026 AIAA Essay Contest
The NASA AIAA Essay Contest is one of the most competitive aerospace science writing competitions available to student researchers, organized by the American Institute of Aeronautics and Astronautics. Aryash took first place in the 2026 contest, demonstrating not only mastery of aerospace concepts but the ability to construct a rigorous, original scientific argument for a demanding expert audience. The win reflects the same combination of analytical depth and clear communication that defines his work across research, broadcasting, and documentary filmmaking.
Curious About Aryash's Work?
Whether you're a journalist, or a fellow scientist, Aryash welcomes the conversation. Visit the Connect page to send a message, request a press kit, or learn more about any of these projects.